News

News selection

In the following you will find news from Polypharma Technologies & Sciences GmbH and the pharmaceutical industry.

Sodium Alendronate as drinking solution and effervescent tablet

Sodium alendronate, which belongs to the group of biphosphonates, has been released as a new drinking solution on the French market. The drinkable solution is easy to take and is quickly absorbed. The active substance is indicated for postmenopausal osteoporosis and reduces the risk of vertebral and hip fractures.

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EU approval of the first triple combination for asthma

The drug belonging to the DPI group administered in hard capsules consists of the ingredients indacaterol/glycopyrronium/mometasone (114 µg / 46 µg / 68 µg). This fixed tri-therapy is used in patients with insufficiently controlled asthma with a combination of a long-acting beta-2 agonist (LABA) and a high dose of an inhaled corticosteroid (ICS) as maintenance therapy and in which at least one exaceration occurred in the previous year. After 26 weeks of treatment, the maximum air volume that...

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New oral formulation with Diclofenac

In France, 50 mg of diclofenac epolamine granules for oral suspension in sachets have been granted marketing authorisation and are now available. The field of application extends over: short-term symptomatic treatment of acute seizures of extraarticular rheumatism such as scapulo-humerus periarthritis, tendonitis and mucosal inflammation in adolescents (over 15 years of age) and adults; microcrystalline arthritis; arthritis; Low Back Pain (lumbago); Radiculalgia

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To what extent is penicillin allergy present and what alternative antibiotic treatment is possible?

As a cohort study of 106 US hospitals between 09/2018 and 01/2019 has shown, it is primarily important to check whether there really is a penicillin allergy at the time of the disease. In most cases, the allergy was already present some time ago and may have already disappeared. fter alternative testing with 1) ß-lactam antibiotic alternatives, such as macrolides, sulphonamides, tetracyclines, clindamycin and linezolid, 2) narrow-spectrum ß-lactam antibiotics, such as 1st/2nd generation...

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Points to be taken into consideration in human medicine in the paediatric field

There are several points to consider if you want to offer paediatric medicines in addition to products for adults. Paediatrics distinguishes between the categories: newborns, infants, children and adolescents. This means that you may need four different products, or the occurring diseases may also vary by age group. With the chosen formulation, it is important to choose a dosage by weight, after drug release of the correct dosage form. Polypharma also has paediatric dossiers in its portfolio...

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Metal Detector for Tablets and Capsules

At first glance, metal detectors seem to be a good way to promote the safety of your own products. But is it an essential machine or a "nice to have"? The detectors are used to detect metal pieces e.g. of a sieve in a tablet/capsule that has torn during production and to sort them out. In your risk assessment you should note which case can lead to metal pieces in the end product and how often the case occurs. If the case of a cracked sieve in production occurs every 5 years and a purchase of a...

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Why a market analysis of your own market is so important

A market analysis is usually considered superfluous, here are a few reasons to change your mind: Markets and customers, and/or the top 10 diseases are changing: A market analysis helps to uncover the sometimes slow, sometimes fast changes in the market and not to lose sight of them. The market analysis method must be properly structured. What is the most expensive analysis if the right parameters are not recorded? Expertise in healthcare. Any market analysis does not help you if you do not...

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Nitrosamine Impurities

In 2018, nitrosamine impurities were detected in the blood pressure medication of the Sartane group. Nitrosamines are potentially carcinogenic. Although the risk of these compounds being carcinogenic to humans is very low, the European Medicines Agency (EMA) has called for the holders of marketing authorisations for placing these raw materials on the EU market to undergo analyses. These analyses are intended to determine the extent to which the raw materials or manufacturing conditions may...

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Time and cost savings when purchasing machines

We have added a section on machine acquisition to our generic dictionary. This includes the 5 most important points when purchasing a machine: Delivery times of equipment Is everything available for the machine installation? Procurement book Machine validation Lead times to production and loss of production

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Effects of the consumption of dairy products on the metabolic syndrome

The "Prospective Urban Rural Epidemiology" (PURE) study examined whether there is an association between the daily consumption of dairy products and the metabolic syndrome, arterial hypertension and type II diabetes. The metabolic syndrome exhibits the following pathologies: high blood pressure, abdominal obesity, elevated triglycerides, low HDL cholesterol and elevated blood glucose. This syndrome leads to an increased risk of cardiovascular disease, type II diabetes and increased mortality....

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Polypharma
Technologies & Sciences GmbH

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20457 Hamburg
Germany
+49 (0)40 37 480 3-0
info[at]polypharma.de