News
News selection
In the following you will find news from Polypharma Technologies & Sciences GmbH and the pharmaceutical industry.
Solriamfetol film-coated tablets for narcolepsy and sleep apnea
A new drug for the treatment of narcolepsy and obstructive sleep apnea is coming to market in Germany in the form of Solriamfetol 75mg and 150mg film-coated tablets. Solriamfetol is a psychoanaleptic that inhibits the reuptake of dopamine and noradrenaline. http://news.gelbe-liste.de/c/33246521/7c295f2a515a1-1fc7bog
Clinical tests of biosimilars in comparison to biopharmaceuticals
Phase 3 clinical trials of biosimilars are beneficial for patients because they do not have to be afraid of receiving a placebo. They receive either the reference product or the biosimilar, so that they receive treatment in any case. In addition, it may be interesting for biosimilar developers to have studies conducted in countries where the price-performance ratio is better. Depending on the country, this can also be a great advantage for patients, as the study in their country creates access...
Thiocolchicoside 4mg capsules
Polypharma has recently developed Thiocolchicoside 4mg capsules. Thiocolchicoside is a muscle relaxant with anti-inflammatory, analgesic and antispasmodic effects. It acts as a competitive GABAA receptor antagonist and also as a glycine receptor antagonist and to a lesser extent as a nicotinic acetylcholine receptor.
Dapagliflozin 5mg and 10mg film-coated tablet helps with heart failure
The SGLT-2 inhibitor (sodium-glucose cotransporter 2) dapagliflozin counteracts progression of heart failure and death of cardiovascular cause in heart failure patients with impaired left ventricular function, regardless of diabetes status. SGLT-2 inhibitors are currently approved for the treatment of type-II diabetes mellitus. https://www.gelbe-liste.de/kardiologie/dapagliflozin-herzinsuffizienz
New paracetamol- and caffeine-based analgesic
Paracetamol (500mg) and caffeine (50mg) tablets are used for the symptomatic treatment of pain of mild to moderate intensity and/or febrile conditions. These may be permitted for adults and children weighing 50kg or more (15 years and older) and may be issued without a doctor's prescription. https://www.vidal.fr/actualites/imprimer/24833/prontadol_adultes_nouveau_medicament_antalgique_a_base_de_paracetamol_et_de_%E2%80%A6
Application of Terbinafine in pregnancy
In a nationwide, register-based cohort study in Denmark with data from two decades, scientists did not find an increased risk of severe malformations or spontaneous abortions when Terbinafine had been used orally or topically during pregnancy. https://www.gelbe-liste.de/gynaekologie/terbinafin-schwangeschaft-sicherheit
Clinical trial of a COVID-19 vaccine approved in Germany
In a press release today, the Paul Ehrlich Institute (PEI) announced that it has approved the first clinical trial of a vaccine against COVID-19 in Germany. It is a ribonucleic acid (RNA) vaccine. https://www.gelbe-liste.de/nachrichten/corona-impfstoff-klinische-studie
Givosarin 189mg/ml solution for injection
Givosiran 189mg/ml solution for injection is the first drug approved in Europe for the treatment of acute hepatic porphyria (AHP). It is an RNAi drug with which a gene can be silenced. Until now, there has been no approved drug therapy for patients with AHP. https://www.gelbe-liste.de/neue-medikamente/givlaari-givorisan-hepatische-porphyrie
Ascorbic acid shortens the duration of mechanical ventilation in patients
The review published in the Journal of Intensive Care : "Vitamin C may reduce the duration of mechanical ventilation in critically ill patients: a meta-regression analysis" postulates that vitamin C (Ascorbic acid) can shorten the duration of mechanical ventilation in critically ill patients by an average of 25 percent. Without supplementation, plasma vitamin C levels are particularly low in critically ill patients. The more ill a patient is, the higher the consumption of vitamin C apparently...
Strengthening the lymphatic system means: Supporting the immune system
The lymph vessel system runs through the whole body and is responsible, among other things, for the drainage of tissue. The most obvious task of the lymphatic system for us is the defence function. The lymphatic organs - such as lymph nodes, tonsils and thymus - are important switching points of the immune system and the lymphocytes are the immune cells. A well-functioning lymphatic system is an essential prerequisite for good defences....
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